Kilimanjaro Christian Medical centre
moshi, tanzania
RECENT Research PUBLICATIONS
Kelly C, Nisar M, Arthanari S, Carty S, Woodhead F, Price-Forbes A, et al, Rheumatoid arthritis related interstitial lung disease – improving outcomes over 25 years: a large multicentre UK study. Rheumatology, 2020, keaa577, https://doi.org/10.1093/rheumatology/keaa577.
Elinisa M, Lugata S, Doshi B, Kelly CA, Ngocho JS. Journal of Mental Health. Symptoms and predictors of depression among university students in the Kilimanjaro region of Tanzania: a cross-sectional study. J Mental Health 2020 https://www.tandfonline.com/eprint/J42TTPRHBG6FJ4KEIG8K/full?target=10.1080/09638237.2020.1793129
Williamson, J, Black, L, Black, A, Koduri G and Kelly CA. Similarities between rheumatic disease with lung involvement and COVID-19 pneumonia. Irish J Med Sci (2021). https://doi.org/10.1007/s11845-021-02545-y
Kelly CM, Kelly CA. What is Different about Eating Disorders for Those with Autistic Spectrum Condition? Int J Psychiatric Res. 2021; 4(1): 1-8. https://www.scivisionpub.com/previousdisplay.php?journal=svijpr&&v=4&&i=2&&y=2021&&m=April
Hickey P, Hogg E and Kelly CA. Mental health in young people and the potential benefits of social media. Minerva Psychiatry March 2021; 02:
Raw RK, Kelly C, Rees J, Wroe C and Chadwick D. Previous COVID-19 infection, but not Long-COVID, is associated with increased adverse events following BNT162b2/Pfizer vaccination. J Infection 2021 DOI:10.1101/2021.04.15.21252192 ID: 233346080
Kelly C, Dieude P and Emery P. Unmet needs in rheumatoid arthritis related interstitial lung disease. Lancet Rheumatology July 2021, 3 (11). DOI: 10.1016/S2665-9913(21)00250-2
Scarlett R, Kelly C. Prevalence and Correlates of Depression during the COVID-19 Epidemic among Undergraduate Students in the United Kingdom. Anxiety And Depression Journal. 2021; 4(1):127
Matteson E, Kelly C, Distler J et al. Nintedanib in patients with autoimmune disease-related progressive fibrosing interstitial lung diseases: subgroup analysis of the INBUILD trial. Arthritis Rheumatol 2022; 74: 1039-1047. 23 February 2022. https://doi.org/10.1002/art.42075
Kelly C, Martin R and Saravanan V. The links between fibromyalgia, hypermobility and neurodivergence. TouchReviews March 15th 2022 https://www.touchimmunology.com/fibromyalgia/journal-articles/the-links-between-fibromyalgia-hypermobility-and-neurodivergence/
Walsh R, Mwingwa A, Yongolo N, Biswaro S, Mwanswila M, Kelly C et al (2022) The spectrum and burden of in-patient paediatric musculoskeletal diseases in Northern Tanzania, Paediatrics and International Child Health, DOI: 10.1080/20469047.2022.2062561
Clive Kelly. COMMENTARY ON THE INCREASED RISK OF SEVERE COVID-19 IN RA PATIENTS. Lancet Rheumatology. Published Online September 13, 2022 https://doi.org/10.1016/ S2665-9913(22)00256-9
Yongolo N, Bunn C, Halliday J, Mtesha B, Kelly C, Mwingwa A, et al. Estimating the prevalence and predictors of musculoskeletal disability in Tanzania: a pilot study, Rheumatology, Volume 61, Issue Supplement_1, May 2022, keac133.097, https://doi.org/10.1093/rheumatology/keac133.097
Yongolo N, Krauth S, Biswaro S, Moshi B, Mwanswila M, Hemed A, et al. A retrospective survey of arthritis among inpatients at a consultant hospital in Northern Tanzania from 2017 to 2019, Rheumatology, Volume 61, Issue Supplement_1, May 2022, P208 keac133.207, https://doi.org/10.1093/rheumatology/keac133.207
Krauth S, Yongolo N, Biswaro S, Kelly C, Walker R, Siebert S, et al., NIHR Global health Research Group on Arthritis in Tanzania, Prevalence and associated factors of musculoskeletal joint disease in the community setting in Hai district, northern Tanzania, Rheumatology, Volume 61, Issue Supplement_1, 105; May 2022, keac133.104, https://doi.org/10.1093/rheumatology/keac133.104
Garton M and Kelly C. Are JAK inhibitors the future of RA-ILD treatment? Touch Reviews December 2022. Published Online: December 8th 2022touchREVIEWS in Respiratory & Pulmonary Diseases. 2022;7(2):38–40. Is Janus Kinase Inhibition the Future of the Management of Rheumatoid Arthritis-associated Interstitial Lung Disease? - touchRESPIRATORY
Ryan L, Thomson E, Beer H, Philcox E and Kelly CA. AUTISTIC TRAITS CORRELATE WITH CHRONIC MUSCULOSKELETAL PAIN: A SELF-SELECTED POPULATION BASED SURVEY. OBM Neurobiology 2023, Volume 7, Issue 1, doi:10.21926/obm.neurobiol.2301155 16 February 2023
Kuo C, Black L, Barber S and Kelly CA. Arthritis in East Africa. African Journal Rheumatol 28 Feb 2023 Vol. 11 No. 1 (2023), pages 3 – 9.
Koduri G, Podlasek A, Pattapola S, Laila D, Nandagudi A, Dubey S, Kelly C. Four-factor risk score for the prediction of interstitial lung disease in rheumatoid arthritis. Rheumatol Int (2023). https://doi.org/10.1007/s00296-023-05313-6
Clive Kelly. Joining the dots: providing medical and humanitarian assistance in East Africa. RCP Commentary March 2023, pages 28-34. Commentary magazine | RCP London
Clive Kelly. The Association between Fibromyalgia, Hypermobility and Neurodivergence Extends To Families: Brief Report. Int J Psychiatr Res. 2023; 6(3): 1-5.
Mmbaga, B. T. et al. (2023) Musculoskeletal (MSK) disorders with arthritis screening in Tanzania: new insights into the growing clinical, economic and societal burden of non-communicable disease. Tanzania Public Health Bulletin, 10(1), pp. 8-14.
Clive Kelly. The dangers of being a good Samaritan. Published in ‘Voice of Doctors’ October 2023 Blog - Protecting Medics (voiceofdoctors.org)
Garton M and Kelly CA. Does reduced cathepsin activity contribute to skin and lung fibrosis in patients with systemic sclerosis and related disorders? 13th October 2023 Rheumatology, kead549, https://doi.org/10.1093/rheumatology/kead549
Thomson E, Beer H, Ryan L, Philcox E, Kelly C. Food intolerance and sensitivity are associated with features of fibromyalgia in a self-selected community population. Food Health. 2023;5(4):17. doi:10.53388/FH2023017
Said S, Omar N, Juma F, and Kelly CA. Clinical, serological and radiological findings in patients with rheumatoid arthritis from Zanzibar comparing those with and without interstitial lung disease Trends in Immunotherapy (2023) Volume 7 Issue 2. https://doi: 10.24294/ti.v7.i2.2716
Martin R, Taylor R, Kelly CA. Recognising the rheumatological needs of neurodivergent females: COMMENTARY. Rheumato, November 2023, 3(4), 221-227; https://doi.org/10.3390/rheumato3040017
Dr Clive Kelly. Surviving a referral to the GMC. ‘RCP Commentary’ 2023. December 3rd 2023, 32-34.
Kilonzo K, Krauth S, Halliday J, Kelly C, Siebert S, Temu G et al. Estimating the prevalence, quality of life, economic and societal impact of arthritis in Tanzania: protocol for a mixed methods study. 2023 Doi.org/10.17504/protocols.io.8epv5j8r4l1b/v1
Kelly C. International Clinicians and Academics Supporting the Refugee Journey- personal narratives from the field. Qeios 2023 https://qeios.com/read/RWM24L.12 International Clinicians and Academics Supporting the Refugee Journey- personal narratives from the field. - Article (Preprint v12) by Clive Kelly | Qeios
Juge P, Granger B, El Houari L, McDermott G, Doyle T, Kelly CA et al. Déchiffrer la pneumopathie interstitielle diffuse associée à la polyarthrite rhumatoïde en utilisant une analyse en cluster hiérarchique non supervisée : résultats d’une collaboration internationale. Revue du Rhumatisme Volume 90, Supplement 1, December 2023, Pages A27-A28 https://doi.org/10.1016/j.rhum.2023.10.040
Mark Garton, Clive Kelly, Does reduced cathepsin activity contribute to skin and lung fibrosis in patients with systemic sclerosis and related disorders?, Rheumatology, Volume 63, Issue 3, March 2024, Pages e81–e82, https://doi.org/10.1093/rheumatology/kead549
Kelly C, Taylor R, Martin R, Doherty M. Recognising and responding to physical and mental health issues in neurodivergent girls and women. BJHM 2nd April 2024; Volume 25, issue 4. https://doi.org/10.12968/hmed.2023.0337
Said S, Yongolo N, Biswaro S, Walker R, Kelly C. Decolonisation of health care in East Africa: opinion piece. 24th April 2024. GHES null, 0(0), 2299. https://doi.org/10.36922/ghes.2299
Kelly, C. A., Kelly, C., & Taylor, R. (2024). Review of the Psychosocial Consequences of Attention Deficit Hyperactivity Disorder (ADHD) in Females. European Journal of Medical and Health Sciences, 6(1), 10–20. https://doi.org/10.24018/ejmed.2024.6.1.2033
Kelly CA, Bennett M. Walking to Santiago on the Camino Portuguese: Northern Cross, March 2024, pages 16-17.
Hannah J, Rodziewicz M, Mehta P et al. The diagnosis and management of systemic autoimmune rheumatic disease-related interstitial lung disease: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 18 April 2024. Volume 8, Issue 2, 2024, rkae056, https://doi.org/10.1093/rap/rkae056
Kelly C. The meaning of life: a Himalayan perspective. Northern Cross July 2024, page 23.
Yongolo N, Halliday J, Bunn C, Mtesha B, Kelly CA, Krauth S et al., Estimating the prevalence and predictors of rheumatological disease in the community of northern Tanzania – a pilot study. Pan African Medical Journal 2024; 47: 36 doi: 10.11604/pamj.2024.47.36.38258
Brown K, Chaudhuri N, Corte T, Dieudé P, John L, Kelly C et al. A modified Delphi exercise in physician-perceived risk factors for drug-induced pneumotoxicity in patients with rheumatological disease. BMC Pulmonary Medicine 2024; 24: 547 https://doi.org/10.1186/s12890-024-03287-0
Clive Kelly. Getting to grips with South Sudan. Northern Cross December 2024. Page 12.
Anika Ali and Clive Kelly. Redefining the treatment and rehabilitation of UK prisoners. Qeios Dec 2024.
Dasigan K, Langman K, Iftikhar Z, Kelly CA. Hypermobility and pain – a review of recent developments and their application to clinical practice. Jan 22nd 2025 TouchREVIEWS in RMD. 2025;4(1): DOI: 10.17925/rmd.2025.4.1.4
Deidda M, Grieve E, Krauth S, Hsieh PH, Yongolo N, Siebert S, Halliday J, Biswaro SM, Kilonzo K, Walker R, Kelly C, Msoka EF, Kiula K, Mmbaga B, McIntosh E. Economic burden of musculoskeletal disorders in Tanzania: results from a community-based survey. BMJ Open. 2025 Jan 15;15(1):e087425. doi: 10.1136/bmjopen-2024-087425. PMID: 39819935; PMCID: PMC11751939.
Mwaka L and Kelly C. The rehabilitation of street children in Uganda. Northern Cross. Jan 2025. P18.
IN PRESS
Kelly C, Downs J. Improving understanding, recognition, and treatment for men with anorexia nervosa. BJHM 2025.
Downs J and Kelly C. Medical management and differential diagnosis of restrictive eating disorders in men: considering autism, ARFID and gastroparesis. 2025 International Eating Disorders Journal.
Shaikh M and Kelly C. Editorial: Practical issues relating to the use of anti-fibrotic therapy in patients with interstitial lung disease and rheumatoid arthritis. J Rheumatol 2025
Clive Kelly. Furthering faith in Vietnam. Northern Cross. May 2025.
SUBMITTED
Krauth S, Yongolo N, Biswaro S, Kelly C, Walker R, Siebert S et al., Prevalence and associated factors of musculoskeletal joint disease in the community setting in Hai district, northern Tanzania. Submitted to Lancet Global Health 2024
Kelly CA, Saxena S, Kelly KN. A comparison of physiological adaptation to fast versus slow ascents to 5,300m above sea level. Submitted to Oxygen Nov 2024.
projects based around kilimanjaro
The initial Research program was based around Kilimanjaro Christian Medical Centre in Moshi and the adjacent medical school and Research Institute. We have published and disseminated the results of our work which was the first study to address the prevalence of arthritic conditions in the Tanzanian community and the socio-economic effects thereof. At present we're awaiting the start of a large grant with NIHR via UoG which encompasses a multi-national program to examine the diseases that adversely affect the independence of those people living in Tanzania,Malawi and Ghana. This involves assessing populations for signs of early arthritis, osteoporosis or auto-immune disease. We have learned much about the cause and consequences of diseases here, and understand how auto-immunity and western-style diseases are taking over from infection as one of the biggest threats to well being in this area.
We've also studied the reasons for the high levels of heart disease that affect women after childbirth, and why kidney disease occurs five times more frequently here than in the UK. We suspect that it may take some years to resolve these issues, but anticipate training up local staff to provide an expanded range of services and opportunities in the years to come.
Most recently, we’ve identified high levels of auto-immune disease in Zanzibar, often affecting young people, and we’ve embarked on an ambitious program of research and clinical development to better understand and address these issues.
At the same time, we’re fully aware of the growing number of people with uncontrolled hypertension which is fuelling an epidemic of cerebro- and cardio-vascular disease. Indeed, many of the adult patients who are hospitalised in Africa now have had either heart failure or stroke disease, usually as a result of hypertension. This is another topic of our research program with UK and African Universities.